Guillain-barre Syndrome

Guillain-Barré syndrome is a uncommon healthaffecting also the lungs or the digestive area
situation that affects the nerves outside aprecedes the disorder. The symptoms may live in
person's brain and spinal cord. The peripheralthis stage, causing only meek difficulty in walking,
nerves convey sensory information (e.g., pain,requiring crutches or a walking stick. However,
temperature) from the body to the brain andsometimes the illness progresses, leading to
motor (i.e., movement) signals from the brain tocomplete paralysis of the arms and legs. About 30
the body. Guillain-Barré syndrome is very rare:percent of the people who have the disorder will
It only affects one or two people in everytemporarily require the assist of a machine to
100,000. Most of the people who do getbreathe. Muscle and joint pain can be treated with
Guillain-Barré syndrome recover and are brightover-the-counter analgesics such as aspirin. If
to come back to their normal lives and activities.essential, stronger pain drug may be prescribed.
Guillain-Barre syndrome sometimes is triggered byMuscle spasms can be managed with relaxants
a respiratory disease or the stomach flu.such as diazepam. A new treatment for GBS is
Guillain-Barre syndrome may be an autoimmuneimmunoglobulin therapy. This involves using well
disorder in which the body produces antibodiesantibodies from blood donors to assist block the
that harm the myelin sheath that surroundsharmful antibodies in the body of the person with
peripheral nerves. The myelin sheath is a oily stuffGBS. Plasmapheresis treatment also known as
that surrounds axons. It enlarges the speed atplasma exchange is a type of "blood cleansing" in
which signals travel along the nerves. The primarywhich damaging antibodies are removed from
symptoms of GBS are generally numbness oryour blood. Plasmapheresis consists of removing
tingling (paresthesia) in the toes and fingers, withthe liquid portion of your blood and separating it
progressive weakness in the arms and legs overfrom the actual blood cells. Treatment with
the next few days. Several patients experienceplasmapheresis or intravenous immunoglobulin
paresthesia only in their toes and legs; others onlyshortens the time period before recovery begins
experience symptoms on one side of the body.by as much as 50 percent.
In about 60 percent of the cases, an infection